Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Stxbp3tm1Yt
Name:	syntaxin binding protein 3; targeted mutation 1, Yoshikazu Tamori
MGI ID:	MGI:3528591
Synonyms:	Munc18c-
Gene:	Stxbp3  Location: Chr3:108700496-108747818 bp, - strand  Genetic Position: Chr3, 47.73 cM, cytoband F3
Alliance:	Stxbp3tm1Yt page

Germline Transmission:	Earliest citation of germline transmission: J:95938
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129P/Ola

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A IRES-neo cassette replaced the exon containing the transcription start site. Northern and Western blot analyses confirmed the absence of transcript and protein, respectively, in mutants. (J:95938)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Stxbp3 Mutation:	22 strains or lines available

Original:	J:95938 Kanda H, et al., Adipocytes from Munc18c-null mice show increased sensitivity to insulin-stimulated GLUT4 externalization. J Clin Invest. 2005 Feb;115(2):291-301
All:	1 reference(s)