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Bag1tm1Msd
Targeted Allele Detail
Summary
Symbol: Bag1tm1Msd
Name: BCL2-associated athanogene 1; targeted mutation 1, Michael Sendtner
MGI ID: MGI:3528234
Synonyms: Bag1-, BAG-1-, Bag1tm1Urr
Gene: Bag1  Location: Chr4:40936398-40948294 bp, - strand  Genetic Position: Chr4, 20.67 cM, cytoband B1
Alliance: Bag1tm1Msd page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:95491
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    A neo replaced exons 1 and 2. Western blot demonstrated the lack of protein in mutant lungs. (J:101397)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bag1 Mutation:  20 strains or lines available
References
Original:  J:95491 Gotz R, et al., BAG-1 haplo-insufficiency impairs lung tumorigenesis. BMC Cancer. 2004 Nov 24;4(1):85
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory