Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol: Krt90whnl Name: keratin 90; witch nails MGI ID: MGI:3526848 Gene: Krt90  Location: Chr15:101460791-101471385 bp, - strand  Genetic Position: Chr15, 56.9 cM Alliance: Krt90whnl page

Rear paw of Krt90whnl/Krt90whnl mouse showing very long nails Show the 3 phenotype image(s) involving this allele.

Strain of Origin:

MRL/MpJ-Faslpr/J

Allele Type:    Spontaneous (Not Specified) Mutation:    Duplication   Mutation details: This spontaneous 7 base pair duplication insertion of AGCCTGT in exon 9 causes a serine to arginine substitution at amino acid 476 followed by a frameshift leading to 36 novel amino acids and then a premature stop codon. (J:222308) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Krt90 Mutation:	29 strains or lines available

Original:	J:223505 Ward-Bailey PF, et al., Witch nails (whnl): a new spontaneous mutation that causes very long toenails. MGI Direct Data Submission. 2015;
All:	3 reference(s)