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Tg(Gh-Gal)4599Vron
Transgene Detail
Summary
Symbol: Tg(Gh-Gal)4599Vron
Name: transgene insertion 4599, M E Vrontakis
MGI ID: MGI:3524994
Synonyms: galanin, GAL-Tg, Tg(Gh-Gal)#Vron
Transgene: Tg(Gh-Gal)4599Vron  Location: unknown  
Alliance: Tg(Gh-Gal)4599Vron page
Transgene
origin
Strain of Origin:  C57BL/6 or SJL
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Gh-Gal)4599Vron expresses 1 gene
 
Mutation detailsThe rat preprogalanin full length cDNA, including the polyA tail was cloned downstream of a 320 bp fragment containing the rat Gh promoter. Transgene expression was observed in the pituitary, but was not observed in the ovary, testis, spleen, liver or fat. (J:86486)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Tumor Data
List all tumor models in MMHCdb carrying Tg(Gh-Gal)4599Vron
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:86486 Perumal P, et al., Transgenic mice over-expressing galanin exhibit pituitary adenomas and increased secretion of galanin, prolactin and growth hormone. J Endocrinol. 2003 Nov;179(2):145-54
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory