Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Cacng4tm1Frk
Name:	calcium channel, voltage-dependent, gamma subunit 4; targeted mutation 1, Wayne N Frankel
MGI ID:	MGI:3521945
Synonyms:	g4tml
Gene:	Cacng4  Location: Chr11:107623183-107685383 bp, - strand  Genetic Position: Chr11, 70.29 cM, cytoband E1
Alliance:	Cacng4tm1Frk page

Germline Transmission:	Earliest citation of germline transmission: J:96506
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout, Reporter) Mutation:    Insertion   Mutation details: A lacZ gene was inserted in frame into exon 4 of the gene. A fusion protein consisting of part of Cacng4 and beta-galactosidase is expressed from this allele. (J:96506)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

17 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cacng4 Mutation:	15 strains or lines available

Original:	J:96506 Letts VA, et al., A targeted mutation in Cacng4 exacerbates spike-wave seizures in stargazer (Cacng2) mice. Proc Natl Acad Sci U S A. 2005 Feb 8;102(6):2123-8
All:	1 reference(s)