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Nr2f1tm1Mist
Targeted Allele Detail
Summary
Symbol: Nr2f1tm1Mist
Name: nuclear receptor subfamily 2, group F, member 1; targeted mutation 1, Michele Studer
MGI ID: MGI:3521756
Synonyms: COUP-TF1null
Gene: Nr2f1  Location: Chr13:78337090-78346954 bp, - strand  Genetic Position: Chr13, 41.38 cM
Alliance: Nr2f1tm1Mist page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:114098
Parent Cell Line:  TBV2 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
    Exon 3 was flanked by loxP sites and removed via transient cre expression. (J:114098)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 5 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Nr2f1 Mutation:  24 strains or lines available
References
Original:  J:114098 Armentano M, et al., COUP-TFI is required for the formation of commissural projections in the forebrain by regulating axonal growth. Development. 2006 Nov;133(21):4151-62
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory