Summary | Transgene origin | Transgene description | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Tg(IRS1)1Mhep
Name:	transgene insertion 1, Rolf Carlson
MGI ID:	MGI:3056765
Transgene:	Tg(IRS1)1Mhep  Location: unknown
Alliance:	Tg(IRS1)1Mhep page

Strain of Origin:

FVB

Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence) Mutation:    Insertion   Tg(IRS1)1Mhep expresses 1 gene Transgene expresses: Organism Expressed Gene Homolog in Mouse Note human IRS1 (3667) Irs1  (MGI:99454)   Mutation details: The transgene contains the human insulin receptor substrate 1 (IRS1) gene. Mice overexpress human IRS1 in the liver. (J:92999)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:92999 Tanaka S, et al., Biological effects of human insulin receptor substrate-1 overexpression in hepatocytes. Hepatology. 1997 Sep;26(3):598-604
All:	3 reference(s)