Summary | Transgene origin | Transgene description | Phenotypes | Disease models | Tumor data | Find Mice (IMSR) | References

Symbol:	Tg(WapTgfa)215Bri
Name:	transgene insertion 215, Ralph L Brinster
MGI ID:	MGI:3054253
Synonyms:	TgN(WapTgfa)215Bri, WAP-TGF-alpha line 3573-2
Transgene:	Tg(WapTgfa)215Bri  Location: unknown
Alliance:	Tg(WapTgfa)215Bri page

Strain of Origin:

(C57BL/6 x SJL)F2

Transgene Type:    Transgenic (Inserted expressed sequence) Mutation:    Insertion   Tg(WapTgfa)215Bri expresses 1 gene Transgene expresses: Organism Expressed Gene Homolog in Mouse Note rat Tgfa (24827) Tgfa  (MGI:98724)   Mutation details: The transgene contains the mouse whey acidic protein (WAP) promoter and the mouse transforming growth factor alpha (Tgfa) gene. (J:56318)

View phenotypes and curated references for all genotypes (concatenated display).

List all tumor models in MMHCdb carrying Tg(WapTgfa)215Bri

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:56318 Sandgren EP, et al., Inhibition of mammary gland involution is associated with transforming growth factor alpha but not c-myc-induced tumorigenesis in transgenic mice. Cancer Res. 1995 Sep 1;55(17):3915-27
All:	7 reference(s)