Summary | Transgene origin | Transgene description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(WapIGFBP3)67Dlr
Name:	transgene insertion 67, Derek LeRoith
MGI ID:	MGI:3053842
Transgene:	Tg(WapIGFBP3)67Dlr  Location: unknown
Alliance:	Tg(WapIGFBP3)67Dlr page

Strain of Origin:

(C57BL/6 x SJL)F2

Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence) Mutation:    Insertion   Tg(WapIGFBP3)67Dlr expresses 1 gene Transgene expresses: Organism Expressed Gene Homolog in Mouse Note human IGFBP3 (3486) Igfbp3  (MGI:96438)   Mutation details: The transgene contains the mouse whey acidic protein promoter followed by the complete open reading frame of the human insulin-like growth factor binding protein 3 gene, including 116 bp of 5'UTR sequence and 523 bp of 3'UTR sequence. (J:92578)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:92578 LeRoith D, et al., Insulin-like growth factor-I and insulin-like growth factor binding protein-3 inhibit involution of the mammary gland following lactation: studies in transgenic mice. Prog Growth Factor Res. 1995;6(2-4):433-6
All:	2 reference(s)