Summary | Transgene origin | Transgene description | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	Tg(CAG-lacZ-WGA)330Bbm
Name:	transgene insertion 330, Allan Basbaum
MGI ID:	MGI:3052324
Synonyms:	Tg(ACTB-lacZ-WGA)330Bbm, Tg(CAG-lacZ-WGA)330Bbm, ZW, ZW19
Transgene:	Tg(CAG-lacZ-WGA)330Bbm  Location: unknown
Alliance:	Tg(CAG-lacZ-WGA)330Bbm page

Strain of Origin:

(C57BL/6J x CBA/J)F1

Transgene Type:    Transgenic (Reporter) Mutation:    Insertion   Mutation details: The transgene is comprised of a minimal immediate-early CMV enhancer/chicken beta-actin promoter driving ubiquitous expression of a lox-P flanked beta-galactosidase/neomycin phosphotransferase II (beta-geo) fusion gene that terminates in a strong, triple polyadenylation signal, followed by a C-terminally truncated wheat germ agglutinin coding sequence. Neuron-specific excision of the beta-geo gene by cre recombinase permits expression of the lectin, whose migration allows tracing of synapses involving the expressing cells. (J:92042)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:92042 Braz JM, et al., Transneuronal tracing of diverse CNS circuits by Cre-mediated induction of wheat germ agglutinin in transgenic mice. Proc Natl Acad Sci U S A. 2002 Nov 12;99(23):15148-53
All:	3 reference(s)