Daxxtm1Maul
Targeted Allele Detail
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| Symbol: |
Daxxtm1Maul |
| Name: |
Fas death domain-associated protein; targeted mutation 1, Gerd G Maul |
| MGI ID: |
MGI:3051780 |
| Synonyms: |
Daxx- |
| Gene: |
Daxx Location: Chr17:34128388-34134564 bp, + strand Genetic Position: Chr17, 17.98 cM
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| Alliance: |
Daxxtm1Maul page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:91881
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
129/Sv
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A neomycin resistance gene replaced part of exon 3 and all of exons 4-7, eliminating the last 512 amino acids. The first 227 amino acids were putatively unstable as no transcript was detected in Northern or Western blot. PCR of cell lines confirmed recombination in mutants.
(J:91881)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Daxx Mutation: |
33 strains or lines available
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| Original: |
J:91881 Ishov AM, et al., Heterochromatin and ND10 are cell-cycle regulated and phosphorylation-dependent alternate nuclear sites of the transcription repressor Daxx and SWI/SNF protein ATRX. J Cell Sci. 2004 Sep 1;117(Pt 17):3807-20 |
| All: |
1 reference(s) |
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Analysis Tools
