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Or8a1tm20Mom
Targeted Allele Detail
Summary
Symbol: Or8a1tm20Mom
Name: olfactory receptor family 8 subfamily A member 1; targeted mutation 20, Peter Mombaerts
MGI ID: MGI:3047227
Synonyms: M71(deltaM71)-IRES-taulacZ
Gene: Or8a1  Location: Chr9:37641273-37642357 bp, - strand  Genetic Position: Chr9, 20.8 cM
Alliance: Or8a1tm20Mom page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:91160
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe 3rd bp (G) from the initiation methionine was deleted. No upstream ATGs were created in-frame, leaving the next potential ATG in the coding region at position 115, which would result in a protein truncated by 38 amino acids. An IRES-taulacZ was incorporated downstream of the coding sequence. (J:91160)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Or8a1 Mutation:  69 strains or lines available
References
Original:  J:91160 Feinstein P, et al., Axon guidance of mouse olfactory sensory neurons by odorant receptors and the beta2 adrenergic receptor. Cell. 2004 Jun 11;117(6):833-46
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory