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Gene Expression Data
Assay Details
Assay
Reference: J:41469 Loftus SK, et al., Murine model of Niemann-Pick C disease: mutation in a cholesterol homeostasis gene [see comments]. Science. 1997 Jul 11;277(5323):232-5
Assay type: Northern blot
MGI Accession ID: MGI:3046306
Gene symbol: Npc1
Gene name: NPC intracellular cholesterol transporter 1
Probe: Npc1 cDNA2
Probe preparation: Double stranded DNA
Results Image: 2B
 Sample Information Bands Other Sample Information
Lane AgeStructure 5.8 kb (a) Amount Genetic BackgroundMutant Allele(s)Sex
+/+ P w 8 TS28: liver Present Not Specified; total RNA Not Specified Not Specified
npcnih/npcnih P w 8 TS28: liver Present Not Specified; total RNA BALB/cStCrlfC3HfNctr Npc1m1N/Npc1m1NNot Specified
spm/spm P w 8 TS28: liver Present Not Specified; total RNA involves: C57BLKS/J Npc1spm/Npc1spmNot Specified
+/+ P w 8 TS28: brain Present Not Specified; total RNA Not Specified Not Specified
npcnih/npcnih P w 8 TS28: brain Present Not Specified; total RNA BALB/cStCrlfC3HfNctr Npc1m1N/Npc1m1NNot Specified
Notes:
(a) The expression levels seen in the mutants were reduced compared to those seen in the wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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