Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Or8a1tm6Mom
Name:	olfactory receptor family 8 subfamily A member 1; targeted mutation 6, Peter Mombaerts
MGI ID:	MGI:3045144
Synonyms:	Hyb F, M71-M72 hybrid F
Gene:	Or8a1  Location: Chr9:37641273-37642357 bp, - strand  Genetic Position: Chr9, 20.8 cM
Alliance:	Or8a1tm6Mom page

Germline Transmission:	Earliest citation of germline transmission: J:90716
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Inserted expressed sequence, Reporter) Mutation:    Insertion   Or8a1tm6Mom expresses 1 gene Knock-in expresses: Organism Expressed Gene Note mouse Or8a1b (MGI:1931271)   Mutation details: Six bp changes resulting in 4 amino acid substitutions (T2A, G15R, A146V, V151M) and an IRES-tauGFP gene were introduced via homologous recombination. The resulting protein is a hybrid between Olfr151 and Olfr160 which have a total of 25 bp and 11 amino acid differences. The GFP gene was fused after the stop codon and co-expressed with the mutant protein. (J:90716)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Or8a1 Mutation:	69 strains or lines available

Original:	J:90716 Feinstein P, et al., A contextual model for axonal sorting into glomeruli in the mouse olfactory system. Cell. 2004 Jun 11;117(6):817-31
All:	1 reference(s)