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Dll1tm1Mjo
Targeted Allele Detail
Summary
Symbol: Dll1tm1Mjo
Name: delta like canonical Notch ligand 1; targeted mutation 1, Michael J Owen
MGI ID: MGI:3044907
Synonyms: Dll1lox, Dll1loxP
Gene: Dll1  Location: Chr17:15587616-15597134 bp, - strand  Genetic Position: Chr17, 8.95 cM
Alliance: Dll1tm1Mjo page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:90630
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    Exons 3 and 4 were floxed following the transient cre-mediated excision of a floxed neo. (J:90630)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 25 assay results
In Structures Affected by this Mutation: 6 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Dll1 Mutation:  46 strains or lines available
References
Original:  J:90630 Hozumi K, et al., Delta-like 1 is necessary for the generation of marginal zone B cells but not T cells in vivo. Nat Immunol. 2004 Jul;5(6):638-44
All:  39 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory