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Gene Expression Data
Assay Details
Assay
Reference: J:27756 Verschueren K, et al., Expression of type I and type IB receptors for activin in midgestation mouse embryos suggests distinct functions in organogenesis. Mech Dev. 1995 Jul;52(1):109-23
Assay type: RNA in situ
MGI Accession ID: MGI:3043600
Gene symbol: Acvr1b
Gene name: activin A receptor, type 1B
Probe: ActR-IB cDNA1
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 7A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cerebral cortex Strong Regionally restricted 7A Expression is as a sharp boundary in the anteromedial part.
TS20: diencephalon Strong 7A
TS20: metencephalon floor plate Strong 7A
TS20: medulla oblongata part of 4th ventricle choroid plexus Absent 7A
TS20: metencephalon part of 4th ventricle choroid plexus Absent 7A
TS20: head mesenchyme Absent 7A Expression is absent in the condensation of mesenchyme forming the outer table of the primitive ectomeninx.

Specimen 7B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: trigeminal ganglion Present 7B
TS20: vagus ganglion Present 7B
TS20: vestibulo-cochlear ganglion complex Present 7B
TS20: central nervous system nerve Present 7B Expression is in the facial nerve (VII).
TS20: spinal cord mantle layer Present 7B
TS20: spinal cord marginal layer Present 7B
TS20: neural retinal epithelium Present Regionally restricted 7B Expression is in the inner nuclear layer.

Specimen 7C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: body wall Present 7C
TS20: dorsal root ganglion Present 7C
TS20: olfactory epithelium Present 7C
TS20: pharynx Present 7C
TS20: spinal cord mantle layer Present 7C
TS20: spinal cord marginal layer Present 7C
TS20: vomeronasal organ Present 7C
TS20: mandibular process Present Regionally restricted 7C Expression is in the upper and lower dental lamina.
TS20: maxillary process Present Regionally restricted 7C Expression is in the upper and lower dental lamina.
TS20: oral region Present Regionally restricted 7C Expression is in the submandibular gland.

Specimen 7D: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: dorsal root ganglion Present 7D
TS20: esophagus Present 7D
TS20: spinal cord mantle layer Present 7D
TS20: spinal cord marginal layer Present 7D
TS20: sympathetic ganglion Present Regionally restricted 7D Expression is in the cervico-thoracic ganglion.

Specimen 7E: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: dorsal root ganglion Present 7E
TS20: esophagus Present 7E
TS20: spinal cord mantle layer Present 7E
TS20: spinal cord marginal layer Present 7E
TS20: sympathetic ganglion Present Regionally restricted 7E Expression is in the cervico-thoracic ganglion.

Specimen 7F: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: dorsal root ganglion Present 7F
TS20: hindgut Present 7F
TS20: lung epithelium Present 7F
TS20: midgut Present 7F
TS20: spinal cord mantle layer Present 7F
TS20: spinal cord marginal layer Present 7F
TS20: stomach epithelium Present 7F

Specimen 7G: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: dorsal root ganglion Present 7G
TS20: gonad Present 7G
TS20: hindgut Present 7G
TS20: midgut Present 7G
TS20: pancreas Present 7G
TS20: spinal cord mantle layer Present 7G
TS20: spinal cord marginal layer Present 7G
TS20: ureter Present Regionally restricted 7G Expression is in the epithelial lining of the primitive urethral lumen.

Specimen 7H: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: spinal cord mantle layer Present 7H
TS20: spinal cord marginal layer Present 7H
TS20: telencephalon Present 7H
TS20: axial skeleton Present Regionally restricted 7H Expression is in the intervertebral disks.

Specimen 8A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: body wall Present 8A
TS20: dorsal root ganglion Present 8A
TS20: olfactory epithelium Present 8A

Specimen 8B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: neural retinal epithelium Present Regionally restricted 8B Expression is in the inner nuclear layer.
TS20: body wall Present 8B
TS20: dorsal root ganglion Present 8B
TS20: gonad Present 8B
TS20: hindgut Present 8B
TS20: midgut Present 8B
TS20: pancreas Present 8B
TS20: stomach epithelium Present 8B

Specimen Not Shown: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: pons Strong
TS20: midbrain Strong Regionally restricted Expression is in the tegmentum.
TS20: 4th ventricle Present
TS20: body wall Present
TS20: hypothalamus Present
TS20: inferior glossopharyngeal ganglion Present
TS20: thalamus Present
TS20: head Present Regionally restricted Expression is in the dorsal component of the first branchial arch.
TS20: cerebral cortex Present Regionally restricted Expression is in the region of the future olfactory lobe.
TS20: medulla oblongata part of 4th ventricle choroid plexus Absent
TS20: metencephalon part of 4th ventricle choroid plexus Absent
TS20: head mesenchyme Absent Expression is absent in the condensation of mesenchyme forming the outer table of the primitive ectomeninx.
TS20: endolymphatic sac Absent Expression is absent in the rostral extremity.
TS20: trigeminal nerve Absent


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory