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Tg(tetO-HRAS)72Lc
Transgene Detail
Summary
Symbol: Tg(tetO-HRAS)72Lc
Name: transgene insertion 72, Lynda Chin
MGI ID: MGI:2387693
Synonyms: Tet-Ras
Transgene: Tg(tetO-HRAS)72Lc  Location: unknown  
Alliance: Tg(tetO-HRAS)72Lc page
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Constitutively active, Humanized sequence, Inducible, Inserted expressed sequence)
Inducer:    doxycycline/tetracycline
Mutation:    Insertion
 
Mutation details: The transgene carries a cDNA encoding an activated human HRAS protein (G12V) under the control of a minimal promoter containing multimerized tet-operons. (J:71333)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:71333 Chin L, et al., Essential role for oncogenic Ras in tumour maintenance. Nature. 1999 Jul 29;400(6743):468-72
All:  4 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory