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Taf8Gt(pGT1.8geo)9Pgr
Gene trapped Allele Detail
Summary
Symbol: Taf8Gt(pGT1.8geo)9Pgr
Name: TATA-box binding protein associated factor 8; gene trap 9, Peter Gruss
MGI ID: MGI:3033758
Synonyms: Tbngt
Gene: Taf8  Location: Chr17:47794289-47813216 bp, - strand  Genetic Position: Chr17, 23.33 cM, cytoband C
Alliance: Taf8Gt(pGT1.8geo)9Pgr page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:65596
Parent Cell Line:  MPI-II (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Gene trapped (Null/knockout, Reporter)
Mutation:    Insertion of gene trap vector
 
Mutation detailsA gene trap vector inserted into the endogenous gene such that the lacZ and neomycin genes were fused to the expressed mRNA at position 66. Beta-galactosidase expression was noted in a similar pattern to the wild-type mRNA. (J:65596)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 21 assay results
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Taf8 Mutation:  26 strains or lines available
References
Original:  J:65596 Voss AK, et al., Taube nuss is a novel gene essential for the survival of pluripotent cells of early mouse embryos. Development. 2000 Dec;127(24):5449-61
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory