Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Grxcr1pi-3J
Name:	glutaredoxin, cysteine rich 1; pirouette 3 Jackson
MGI ID:	MGI:3029627
Gene:	Grxcr1  Location: Chr5:68189178-68323741 bp, + strand  Genetic Position: Chr5, 36.59 cM
Alliance:	Grxcr1pi-3J page

Strain of Origin:

BKS.Cg-Dock7m +/+ Leprdb/J

Allele Type:    Spontaneous Mutation:    Intragenic deletion   Mutation details: Genomic PCR demonstrated a deletion with a maximum size of approximately 200 kb that includes exon 1, nearly 125 kb of upstream sequence, and the majority of intron 1. The deletion breakpoint in intron 1 is within 12 kb of exon 2. (J:156811) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Grxcr1 Mutation:	22 strains or lines available

Original:	J:156811 Odeh H, et al., Mutations in Grxcr1 are the basis for inner ear dysfunction in the pirouette mouse. Am J Hum Genet. 2010 Feb 12;86(2):148-60
All:	2 reference(s)