Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Slc25a13tm1Lct
Name:	solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13; targeted mutation 1, Lap-Chee Tsui
MGI ID:	MGI:3028639
Synonyms:	Ctrn -/-
Gene:	Slc25a13  Location: Chr6:6041218-6217173 bp, - strand  Genetic Position: Chr6, 2.3 cM, cytoband A1
Alliance:	Slc25a13tm1Lct page

Germline Transmission:	Earliest citation of germline transmission: J:87578
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A 347 bp region containing exon 10 was replaced with a neomycin resistance gene inserted in opposite orientation. Absence of mRNA transcript was confirmed by Northern blot and absence of protein product by Western blot analysis. (J:87578)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Slc25a13 Mutation:	178 strains or lines available

Original:	J:87578 Sinasac DS, et al., Slc25a13-knockout mice harbor metabolic deficits but fail to display hallmarks of adult-onset type II citrullinemia. Mol Cell Biol. 2004 Jan;24(2):527-36
All:	8 reference(s)