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Scml1 Gene Detail
Summary
  • Symbol
    Scml1
  • Name
    Scm polycomb group protein like 1
  • Synonyms
    LOC195726, LOC386491
Location &
Maps
more
  • Sequence Map
    ChrX:160598170-160608319 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome X, 74.15 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    35 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2684893
protein coding gene ChrX:160597689-160615118 (-)
129S1/SvImJ MGP_129S1SvImJ_G0007573
lincRNA gene ChrX:159785051-159786904 (-)
A/J MGP_AJ_G0007571
lincRNA gene ChrX:159030430-159032283 (-)
AKR/J MGP_AKRJ_G0007541
lincRNA gene ChrX:164096246-164098099 (-)
BALB/cJ MGP_BALBcJ_G0007546
lincRNA gene ChrX:157053258-157055111 (-)
C3H/HeJ MGP_C3HHeJ_G0007493
lincRNA gene ChrX:160172841-160174694 (-)
C57BL/6NJ MGP_C57BL6NJ_G0007719
lincRNA gene ChrX:164534463-164536316 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0006893
lincRNA gene ChrX:150182278-150184293 (-)
CAST/EiJ MGP_CASTEiJ_G0007394
lincRNA gene ChrX:139175273-139177270 (-)
CBA/J MGP_CBAJ_G0007474
lincRNA gene ChrX:169234620-169236473 (-)
DBA/2J MGP_DBA2J_G0007499
lincRNA gene ChrX:157962485-157964338 (-)
FVB/NJ MGP_FVBNJ_G0007515
lincRNA gene ChrX:157091654-157093507 (-)
LP/J MGP_LPJ_G0007579
lincRNA gene ChrX:160982114-160983967 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0007494
lincRNA gene ChrX:177931923-177933776 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0007721
lincRNA gene ChrX:159305648-159307501 (-)
PWK/PhJ MGP_PWKPhJ_G0007331
lincRNA gene ChrX:136013655-136015659 (-)
SPRET/EiJ MGP_SPRETEiJ_G0007235
lincRNA gene ChrX:139607698-139609730 (-)
WSB/EiJ MGP_WSBEiJ_G0007456
lincRNA gene ChrX:157297259-157299256 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    1 phenotype reference
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous or hemizygous for a null mutation are viable and fertile but dense bodies are absent from almost all pachytene spermatocytes.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
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  • All Sequences
  • RefSeq
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000086540 Ensembl Gene Model | MGI Sequence Detail 10150 C57BL/6J ±  kb
transcript ENSMUST00000238615 Ensembl | MGI Sequence Detail 551 Not Applicable  
polypeptide NP_001361133 RefSeq | MGI Sequence Detail 501 C57BL/6  
For the selected sequence
Molecular
Reagents
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  • All nucleic 2
    cDNA 2
Other
Accession IDs
less
MGI:2686638
References
more
  • Summaries
    All 10
    Gene Ontology 1
    Phenotypes 1
  • Earliest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
  • Latest
    J:278848 Papanikos F, et al., The enigmatic meiotic dense body and its newly discovered component, SCML1, are dispensable for fertility and gametogenesis in mice. Chromosoma. 2017 Jun;126(3):399-415

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory