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Sp8tm1Aman
Targeted Allele Detail
Summary
Symbol: Sp8tm1Aman
Name: trans-acting transcription factor 8; targeted mutation 1, Ahmed Mansouri
MGI ID: MGI:2684137
Gene: Sp8  Location: Chr12:118810064-118816311 bp, + strand  Genetic Position: Chr12, 63.48 cM
Alliance: Sp8tm1Aman page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:86325
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Disruption caused by insertion of vector
 
Mutation detailsA sequence fragment from the 5' portion of exon 3 was replaced with a cassette containing lacZ and PGK-neo. (J:86325)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 14 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sp8 Mutation:  29 strains or lines available
References
Original:  J:86325 Treichel D, et al., mBtd is required to maintain signaling during murine limb development. Genes Dev. 2003 Nov 1;17(21):2630-5
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory