Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Pak5tm1Amin
Name:	p21 (RAC1) activated kinase 5; targeted mutation 1 Audrey Minden
MGI ID:	MGI:2679653
Synonyms:	PAK5-
Gene:	Pak5  Location: Chr2:135923024-136229887 bp, - strand  Genetic Position: Chr2, 67.32 cM
Alliance:	Pak5tm1Amin page

Germline Transmission:	Earliest citation of germline transmission: J:85956
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 3 was replaced with a neomycin selection cassette inserted by homologous recombination. Protein was undetected by Western blot analysis of homozygous mutant brain extracts. (J:85956)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

16 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Pak5 Mutation:	37 strains or lines available

Original:	J:85956 Li X, et al., Targeted disruption of the gene for the PAK5 kinase in mice. Mol Cell Biol. 2003 Oct;23(20):7134-42
All:	4 reference(s)