Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Bc1tm1Jbro
Name:	brain cytoplasmic RNA 1; targeted mutation 1, Jurgen Brosius
MGI ID:	MGI:2677614
Gene:	Bc1  Location: Chr7:144468207-144468360 bp, + strand  Genetic Position: Chr7, Syntenic
Alliance:	Bc1tm1Jbro page

Germline Transmission:	Earliest citation of germline transmission: J:85467
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The endogenous gene was replaced with a neomycin selection cassette inserted by homologous recombination. Northern blot analysis confirmed the absence of transcript in homozygous mutant mice. (J:85467)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Bc1 Mutation:	1 strain or line available

Original:	J:85467 Skryabin BV, et al., Neuronal untranslated BC1 RNA: targeted gene elimination in mice. Mol Cell Biol. 2003 Sep;23(18):6435-41
All:	9 reference(s)