Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Bcl3tm1Rie
Name:	B cell leukemia/lymphoma 3; targeted mutation 1, Marc Riemann
MGI ID:	MGI:2675475
Synonyms:	Bcl-3-
Gene:	Bcl3  Location: Chr7:19542387-19556691 bp, - strand  Genetic Position: Chr7, 9.95 cM
Alliance:	Bcl3tm1Rie page

Germline Transmission:	Earliest citation of germline transmission: J:77049
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129/Sv

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin selection cassette replaced sequence encompassing all of exons 3 through 5 and a portion of exon 6. Protein was undetected in homozygous mutant mice by Western blot analysis of spleen whole-cell protein extracts. (J:77049, J:144438)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bcl3 Mutation:	56 strains or lines available

Original:	J:77049 Paxian S, et al., Abnormal organogenesis of Peyer's patches in mice deficient for NF-kappaB1, NF-kappaB2, and Bcl-3. Gastroenterology. 2002 Jun;122(7):1853-68
All:	3 reference(s)