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Gene Expression Data
Assay Details
Assay
Reference: J:84360 Dalvin S, et al., Expression of Netrin-1 and its two receptors DCC and UNC5H2 in the developing mouse lung. Gene Expr Patterns. 2003 Jun;3(3):279-83
Assay type: Immunohistochemistry
MGI Accession ID: MGI:2670868
Gene symbol: Dcc
Gene name: DCC netrin 1 receptor
Antibody: DCC Antibody (A-20): sc-6535
Detection system: Secondary antibody coupled to fluorescein
Results
Specimen 3A,B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: lung epithelium Weak Regionally restricted 3B , 3A Expression is in the epithelium of the major conducting airways.
TS20: lung mesenchyme Present Regionally restricted 3A , 3B Expression is in discrete areas.
Specimen 3C,D: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lung epithelium Present 3D , 3C
TS22: lung mesenchyme Weak 3D , 3C
Specimen 3E,F: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: lung epithelium Present 3E , 3F
TS24: lung mesenchyme Weak 3F , 3E
Specimen 3G,H: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: lung epithelium Weak Regionally restricted 3H , 3G Expression is at the luminal aspect of the bronchiolar epithelium.
Specimen 4A,B,C: embryonic day 12.5 (more )
Note: Double labeled: green - Dcc; red - Unc5b (assay MGI:2670869).
Structure Level Pattern Image Note
TS20: lung epithelium Present 4C , 4A , 4B Expression on the basal and lumenal surfaces overlaps with that of Unc5h2.
Specimen 4D,E,F: embryonic day 14.5 (more )
Note: Double labeled: green - Dcc; red - Unc5b (assay MGI:2670869).
Structure Level Pattern Image Note
TS22: lung epithelium Present 4F , 4E , 4D Expression is on the lumenal surfaces and overlaps with that of Unc5h2.
Specimen 4G,H,I: embryonic day 16.5 (more )
Note: Double labeled: green - Dcc; red - Unc5b (assay MGI:2670869).
Structure Level Pattern Image Note
TS24: lung epithelium Present 4I , 4H , 4G Few epithelial cells express both Unc5h2 and Dcc.
Specimen 4J,K,L: embryonic day 18.5 (more )
Note: Double labeled: green - Dcc; red - Unc5b (assay MGI:2670869).
Structure Level Pattern Image Note
TS26: lung epithelium Present 4J , 4K , 4L Few epithelial cells express both Unc5h2 and Dcc.
Specimen 5C,D: embryonic day 16.5 (more )
Note: Double labeled: green - Dcc; red - Sftpb (assay MGI:2670874).
Structure Level Pattern Image Note
TS24: lung epithelium Present 5C , 5D Expression co-localized with Sftbp in the large airways, but localized differently within the cell.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
MGI 6.23 		The Jackson Laboratory