Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | Notes | References

Symbol:	Foxo3tm1.1Rdp
Name:	forkhead box O3; targeted mutation 1.1, Ronald DePinho
MGI ID:	MGI:2668328
Synonyms:	Foxo3a-
Gene:	Foxo3  Location: Chr10:42057841-42152691 bp, - strand  Genetic Position: Chr10, 22.79 cM
Alliance:	Foxo3tm1.1Rdp page

Germline Transmission:	Earliest citation of germline transmission: J:84269
Parent Cell Line:	TC1/TC-1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The floxed region containing neo and exon 2 was excised from Foxo3tm1Rdp via in vivo cre mediated recombination. Transcript was undetected by Northern blot analysis of homozygous mutant liver tissue. (J:84269)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	38 assay results 2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	6 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Foxo3 Mutation:	48 strains or lines available

Original:	J:84269 Castrillon DH, et al., Suppression of ovarian follicle activation in mice by the transcription factor Foxo3a. Science. 2003 Jul 11;301(5630):215-8
All:	44 reference(s)