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Gene Expression Data
Assay Details
Assay
Reference: J:51536 Reyes JC, et al., Altered control of cellular proliferation in the absence of mammalian brahma (SNF2alpha). EMBO J. 1998 Dec 1;17(23):6979-91
Assay type: Western blot
MGI Accession ID: MGI:2661980
Gene symbol: Smarca4
Gene name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
Antibody: anti-BRG1(N-ter)
Detection system: Secondary antibody
Assay notes: Specific antibody used not specified in reference; assay could have used anti-BRG1(C-ter) (MGI:2661949).
Results Image: 4A BRG1
 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Genetic BackgroundMutant Allele(s)Sex
LIVER WT P adult TS28: liver Present Not Specified Not Specified
LIVER WT P adult TS28: liver Present Not Specified Not Specified
LIVER -/- P adult TS28: liver Present (a) involves: 129S2/SvPas Smarca2tm1Mya/Smarca2tm1MyaNot Specified
LIVER -/- P adult TS28: liver Present (a) involves: 129S2/SvPas Smarca2tm1Mya/Smarca2tm1MyaNot Specified
SPLEEN WT P adult TS28: spleen Present Not Specified Not Specified
SPLEEN WT P adult TS28: spleen Present Not Specified Not Specified
SPLEEN -/- P adult TS28: spleen Present (a) involves: 129S2/SvPas Smarca2tm1Mya/Smarca2tm1MyaNot Specified
SPLEEN -/- P adult TS28: spleen Present (a) involves: 129S2/SvPas Smarca2tm1Mya/Smarca2tm1MyaNot Specified
KIDNEY WT P adult TS28: metanephros Present Not Specified Not Specified
KIDNEY WT P adult TS28: metanephros Present Not Specified Not Specified
KIDNEY -/- P adult TS28: metanephros Present (b) involves: 129S2/SvPas Smarca2tm1Mya/Smarca2tm1MyaNot Specified
KIDNEY -/- P adult TS28: metanephros Present (b) involves: 129S2/SvPas Smarca2tm1Mya/Smarca2tm1MyaNot Specified
BRAIN WT P adult TS28: brain Present Not Specified Not Specified
BRAIN WT P adult TS28: brain Present Not Specified Not Specified
BRAIN -/- P adult TS28: brain Present (c) involves: 129S2/SvPas Smarca2tm1Mya/Smarca2tm1MyaNot Specified
BRAIN -/- P adult TS28: brain Present (c) involves: 129S2/SvPas Smarca2tm1Mya/Smarca2tm1MyaNot Specified
lung wt P adult TS28: lung Present (d) Not Specified Not Specified
lung -/- P adult TS28: lung Present (d) involves: 129S2/SvPas Smarca2tm1Mya/Smarca2tm1MyaNot Specified
thymus wt P adult TS28: thymus Present (d) Not Specified Not Specified
thymus -/- P adult TS28: thymus Present (d) involves: 129S2/SvPas Smarca2tm1Mya/Smarca2tm1MyaNot Specified
heart wt P adult TS28: heart Present (d) Not Specified Not Specified
heart -/- P adult TS28: heart Present (d) involves: 129S2/SvPas Smarca2tm1Mya/Smarca2tm1MyaNot Specified
Notes:
(a) Authors report that levels were 2-fold higher than in wild-type.
(b) Authors report higher levels than in wild-type.
(c) Authors report that levels were 5- to 6-fold higher than in wild-type.
(d) Authors report similar results in lung, thymus and heart (not shown).
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory