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Atrnmg-6J
Spontaneous Allele Detail
Summary
Symbol: Atrnmg-6J
Name: attractin; mahogany 6 Jackson
MGI ID: MGI:2657306
Gene: Atrn  Location: Chr2:130748415-130872253 bp, + strand  Genetic Position: Chr2, 63.26 cM
Alliance: Atrnmg-6J page
Mutation
origin
Strain of Origin:  CAST/EiJ
Mutation
description
Allele Type:    Spontaneous
Mutation:    Intragenic deletion
 
Mutation detailsThis mutation has a genomic deletion which encompasses much of the Atrn gene including the N-terminus, but not the C-terminus. The last two coding exons are not deleted. Northern blot analysis of total brain RNA failed to detect Atrn transcript in mice homozygous for this allele. (J:96070)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 8 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Atrn Mutation:  89 strains or lines available
References
Original:  J:96070 Bronson RT, et al., Mice with mutations in the mahogany gene Atrn have cerebral spongiform changes. J Neuropathol Exp Neurol. 2001 Jul;60(7):724-30
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory