Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Rag2tm1.1Cgn
Name:	recombination activating gene 2; targeted mutation 1.1, University of Cologne
MGI ID:	MGI:2654909
Synonyms:	RAG-2del
Gene:	Rag2  Location: Chr2:101455063-101462874 bp, + strand  Genetic Position: Chr2, 53.87 cM
Alliance:	Rag2tm1.1Cgn page

Germline Transmission:	Earliest citation of germline transmission: J:72214
Parent Cell Line:	Bruce 4 (ES Cell)
Strain of Origin:	B6.Cg-Thy1a

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: This allele is a derivative of Rag2tm1Cgn in which the sequences flanked by loxP sites were deleted in vivo by crossing mice carrying this allele to a deleter strain. (J:72214)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

4 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 4 strains available      Cell Lines: 0 lines available
Carrying any Rag2 Mutation:	117 strains or lines available

Original:	J:72214 Hao Z, et al., Homeostasis of peripheral b cells in the absence of b cell influx from the bone marrow. J Exp Med. 2001 Oct 15;194(8):1151-64
All:	181 reference(s)