Summary | Transgene origin | Transgene description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(APOC1)1Bres
Name:	transgene insertion 1, Jan L Breslow
MGI ID:	MGI:2447788
Transgene:	Tg(APOC1)1Bres  Location: unknown
Alliance:	Tg(APOC1)1Bres page

Strain of Origin:

(C57BL/6J x CBA/J)F2

Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence) Mutation:    Insertion   Tg(APOC1)1Bres expresses 1 gene Transgene expresses: Organism Expressed Gene Homolog in Mouse Note human APOC1 (341) Apoc1  (MGI:88053)   Mutation details: The transgene consists of a liver specific enhancer element and a genomic DNA fragment containing human APOC1 with 3 kb of 5' flanking sequences and 2.5 kb of 3' flanking sequences. RNase protection assay confirmed transgene expression exclusively in the liver. (J:80950)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:80950 Shachter NS, et al., Combined hyperlipidemia in transgenic mice overexpressing human apolipoprotein Cl. J Clin Invest. 1996 Aug 1;98(3):846-55
All:	2 reference(s)