Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Cacnb2tm1Rgg
Name:	calcium channel, voltage-dependent, beta 2 subunit; targeted mutation 1, Ronald G Gregg
MGI ID:	MGI:2429694
Synonyms:	beta2-null, Cavbeta2-
Gene:	Cacnb2  Location: Chr2:14607899-14992719 bp, + strand  Genetic Position: Chr2, 10.7 cM
Alliance:	Cacnb2tm1Rgg page

Germline Transmission:	Earliest citation of germline transmission: J:80080
Parent Cell Line:	AB1 (ES Cell)
Strain of Origin:	129S7/SvEvBrd-Hprt1+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     The gene was disrupted by replacement of exons 4-13 with a PGK-neo cassette. (J:80080)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cacnb2 Mutation:	50 strains or lines available

Original:	J:80080 Ball SL, et al., Role of the beta(2) subunit of voltage-dependent calcium channels in the retinal outer plexiform layer. Invest Ophthalmol Vis Sci. 2002 May;43(5):1595-603
All:	6 reference(s)