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Zrsr2-ps1tm1Mok
Targeted Allele Detail
Summary
Symbol: Zrsr2-ps1tm1Mok
Name: zinc finger (CCCH type), RNA binding motif and serine/arginine rich 2, pseudogene 1; targeted mutation 1, Motoya Katsuki
MGI ID: MGI:2388701
Gene: Zrsr2-ps1  Location: Chr11:22923228-22924514 bp, + strand  Genetic Position: Chr11, 14.24 cM, cytoband A3-4
Alliance: Zrsr2-ps1tm1Mok page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:60421
Parent Cell Line:  CCE/EK.CCE (ES Cell)
Strain of Origin:  129S/SvEv-Gpi1c
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe entire coding region of the gene and 3/4 of the CpG islands including region II (the oocyte-specific methylation sequences), were deleted and replaced with a PGK-gpt-neo cassette via homologous recombination. The targeted mutation was confirmed by Southern blot analysis of tail tip DNA. (J:60421)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Zrsr2-ps1 Mutation:  13 strains or lines available
References
Original:  J:60421 Sunahara S, et al., The oocyte-specific methylated region of the U2afbp-rs/U2af1-rs1 gene is dispensable for its imprinted methylation. Biochem Biophys Res Commun. 2000 Feb 16;268(2):590-5
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory