Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Pde6brd10
Name:	phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide; retinal degeneration 10
MGI ID:	MGI:2388259
Synonyms:	Pde6brd1-J, rd10
Gene:	Pde6b  Location: Chr5:108536239-108579609 bp, + strand  Genetic Position: Chr5, 53.07 cM
Alliance:	Pde6brd10 page

Strain of Origin:

CXB1/ByJ

Allele Type:    Spontaneous Mutation:    Nucleotide substitutions   Mutation details: An initial complementation test with Pde6b rd1 demonstrated allelism. Sequence analysis shows that the rd10 mutation is caused by a missense mutation in exon 13, which encodes the beta subunit of the protein. (J:75095) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pde6b Mutation:	119 strains or lines available

Original:	J:75095 Chang B, et al., Retinal degeneration mutants in the mouse. Vision Res. 2002 Feb;42(4):517-25
All:	155 reference(s)