Tg(Fabpl-CTNNB1)1Jig
Transgene Detail
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| Symbol: |
Tg(Fabpl-CTNNB1)1Jig |
| Name: |
transgene insertion 1, Jeffrey I Gordon |
| MGI ID: |
MGI:2383988 |
| Synonyms: |
deltaN89beta-catenin |
| Transgene: |
Tg(Fabpl-CTNNB1)1Jig Location: unknown
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| Alliance: |
Tg(Fabpl-CTNNB1)1Jig page
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| Mouse Generated: |
Earliest citation of chimera generation:
J:47861
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| Parent Cell Line: |
D3 (ES Cell)
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| Strain of Origin: |
129S2/SvPas
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(Fabpl-CTNNB1)1Jig expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
CTNNB1 (1499) |
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Mutation details: A human CTNNB1 gene deleted for 89 N-terminal amino acids was used for the transgene. Nucleotides -596 to +21 from Fabpl were used to drive expression of the transgene in intestinal epithelium. RT-PCR analysis confirmed the expression of the transgene. Western blot of total jejunal proteins and immunohistochemistry of jejunal sections confirmed transgene protein product in transgenic animals.
(J:47861)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:47861 Wong MH, et al., Effects of forced expression of an NH2-terminal truncated beta-Catenin on mouse intestinal epithelial homeostasis. J Cell Biol. 1998 May 4;141(3):765-77 |
| All: |
1 reference(s) |
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Analysis Tools
