Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Numbtm1Zili
Name:	NUMB endocytic adaptor protein; targeted mutation 1, Olav Zilian
MGI ID:	MGI:2388022
Synonyms:	numbflox, Numbneo-lox
Gene:	Numb  Location: Chr12:83840808-83968708 bp, - strand  Genetic Position: Chr12, 38.89 cM, cytoband D3
Alliance:	Numbtm1Zili page

Germline Transmission:	Earliest citation of germline transmission: J:68652
Parent Cell Line:	GS1 (ES Cell)
Strain of Origin:	129/Sv

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: Exon 1 was flanked with loxP sites by insertion of a floxed PGK-neo cassette and a single loxP site into the upstream and downstream introns, respectively. (J:68652)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	27 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	7 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Numb Mutation:	59 strains or lines available

Original:	J:68652 Zilian O, et al., Multiple roles of mouse Numb in tuning developmental cell fates. Curr Biol. 2001 Apr 3;11(7):494-501
All:	28 reference(s)