Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Gdf7tm1Kng
Name:	growth differentiation factor 7; targeted mutation 1, David M Kingsley
MGI ID:	MGI:2387817
Synonyms:	Gdf7-
Gene:	Gdf7  Location: Chr12:8347918-8351954 bp, - strand  Genetic Position: Chr12, 3.85 cM
Alliance:	Gdf7tm1Kng page

Germline Transmission:	Earliest citation of germline transmission: J:69607
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The entire mature coding region was replaced with a neomycin resistance cassette via homologous recombination. Homozygous mutant animals were identified by PCR genotype analysis. (J:69607)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gdf7 Mutation:	16 strains or lines available

Original:	J:69607 Settle S, et al., The BMP family member Gdf7 is required for seminal vesicle growth, branching morphogenesis, and cytodifferentiation. Dev Biol. 2001 Jun 1;234(1):138-50
All:	5 reference(s)