Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Lhx3tm1Lmgd
Name:	LIM homeobox protein 3; targeted mutation 1, Laboratory of Mammalian Genes and Development, Heiner Westphal
MGI ID:	MGI:2385819
Synonyms:	Lhx3-
Gene:	Lhx3  Location: Chr2:26090224-26098261 bp, - strand  Genetic Position: Chr2, 18.44 cM, cytoband A2-C1
Alliance:	Lhx3tm1Lmgd page

Germline Transmission:	Earliest citation of germline transmission: J:33050
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Sequences encoding the two LIM domains and a portion of the homeodomain were replaced with a neomycin selection cassette. Transcript was undetected by in situ hybridization analysis of mutant embryos. (J:33050)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	54 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Lhx3 Mutation:	25 strains or lines available

Original:	J:33050 Sheng HZ, et al., Specification of pituitary cell lineages by the LIM homeobox gene Lhx3. Science. 1996 May 17;272(5264):1004-7
All:	12 reference(s)