Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Agrptm1Sqn
Name:	agouti related neuropeptide; targeted mutation 1, Su Qian
MGI ID:	MGI:2183577
Synonyms:	Agrp-
Gene:	Agrp  Location: Chr8:106293327-106306477 bp, - strand  Genetic Position: Chr8, 53.04 cM, cytoband D1-D2
Alliance:	Agrptm1Sqn page

Germline Transmission:	Earliest citation of germline transmission: J:78034
Parent Cell Line:	AB2.2 (ES Cell)
Strain of Origin:	129S7/SvEvBrd-Hprt1b-m2

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The entire coding region was replaced with a neomycin selection cassette. Transcript was undetected in homozygous mutant mice via in situ hybridization. (J:78034)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Agrp Mutation:	18 strains or lines available

Original:	J:78034 Qian S, et al., Neither agouti-related protein nor neuropeptide Y is critically required for the regulation of energy homeostasis in mice. Mol Cell Biol. 2002 Jul;22(14):5027-35
All:	14 reference(s)