Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	Ggt5tm1Mwl
Name:	gamma-glutamyltransferase 5; targeted mutation 1, Michael W Lieberman
MGI ID:	MGI:2182354
Synonyms:	GGL-, GGLtm1
Gene:	Ggt5  Location: Chr10:75425174-75453034 bp, + strand  Genetic Position: Chr10, 38.55 cM
Alliance:	Ggt5tm1Mwl page

Germline Transmission:	Earliest citation of germline transmission: J:77691
Parent Cell Line:	AB2.1 (ES Cell)
Strain of Origin:	129S7/SvEvBrd-Hprt1b-m2

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A 500 bp region of the gene including the TATA box and all of exon 1 was replaced with a PGK-neo cassette via homologous recombination. (J:77691)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ggt5 Mutation:	26 strains or lines available

Original:	J:77691 Shi ZZ, et al., Disruption of gamma-glutamyl leukotrienase results in disruption of leukotriene D(4) synthesis in vivo and attenuation of the acute inflammatory response. Mol Cell Biol. 2001 Aug;21(16):5389-95
All:	3 reference(s)