Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Lgals1tm1Rob
Name:	lectin, galactose binding, soluble 1; targeted mutation 1, Elizabeth J Robertson
MGI ID:	MGI:2181809
Synonyms:	gal-1-, gal1-, Lgals1-
Gene:	Lgals1  Location: Chr15:78810925-78814665 bp, + strand  Genetic Position: Chr15, 37.7 cM, cytoband E
Alliance:	Lgals1tm1Rob page

Germline Transmission:	Earliest citation of germline transmission: J:16245
Parent Cell Line:	CCE/EK.CCE (ES Cell)
Strain of Origin:	129S/SvEv-Gpi1c

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 2, encoding the carbohydrate-binding domain, was replaced with a neomycin selection cassette. Western blot analysis and immunostaining of sections showed an absence of encoded protein in muscle tissue obtained from adult homozygous mutant mice. (J:16245)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	21 assay results
In Structures Affected by this Mutation:	5 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 5 strains available      Cell Lines: 0 lines available
Carrying any Lgals1 Mutation:	19 strains or lines available

Original:	J:16245 Poirier F, et al., Normal development of mice carrying a null mutation in the gene encoding the L14 S-type lectin. Development. 1993 Dec;119(4):1229-36
All:	81 reference(s)