Gene Expression Data
Assay Details
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Assay
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Reference:
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J:75943
Laurikkala J, et al., Regulation of hair follicle development by the TNF signal ectodysplasin and its receptor Edar. Development. 2002 May;129(10):2541-53
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:2180522
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Gene symbol:
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Edar
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Gene name:
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ectodysplasin-A receptor
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Probe:
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dl probe
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Probe preparation:
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Antisense labelled with S35 RNA
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Visualized with:
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Autoradiography
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Results
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Specimen
Not shown:
embryonic day 11.0
(more  )
Note: This specimen was from the back.
Specimen
Not shown:
(close  )
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Genetic Background:
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NMRI
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Age:
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embryonic day 11.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Note:
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This specimen was from the back.
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Specimen
1B:
embryonic day 12.0
(more )
Note: This specimen was from the back.
Specimen
1B:
(close )
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Genetic Background:
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NMRI
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Age:
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embryonic day 12.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Note:
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This specimen was from the back.
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Specimen
1D:
embryonic day 14.0
(more )
Specimen
1D:
(close )
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Genetic Background:
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NMRI
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Age:
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embryonic day 14.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: skin |
Present |
Patchy |
1D
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There is intense expression in the placodes; expression is downregulated in the rest of the ectoderm.
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Specimen
1H:
postnatal day 0
(more )
Specimen
1H:
(close )
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Genetic Background:
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NMRI
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Age:
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postnatal day 0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS27: hair follicle |
Very strong |
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1H
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Expression is present in the bulb of stage 3-6 hair follicles.
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Specimen
5I:
embryonic day 13.0
(more )
Specimen
5I:
(close )
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Genetic Background:
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NMRI
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Age:
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embryonic day 13.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: skin |
Present |
Uniform |
5I
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Expression is present throughout the epithelium.
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Specimen
5J:
(close )
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Genetic Background:
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involves: 129S2/SvPas
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Mutant Allele(s):
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Lef1tm1Rug/Lef1tm1Rug
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Age:
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embryonic day 13.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: skin |
Present |
Uniform |
5J
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Expression is present throughout the epithelium.
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Specimen
5K:
embryonic day 17.0
(more )
Specimen
5K:
(close )
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Genetic Background:
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NMRI
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Age:
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embryonic day 17.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS25: hair bulb |
Very strong |
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5K
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There is intense expression in the bulbs of developing tylotrich hair follicles.
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Specimen
5L:
(close )
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Genetic Background:
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involves: 129S2/SvPas
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Mutant Allele(s):
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Lef1tm1Rug/Lef1tm1Rug
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Age:
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embryonic day 17.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS25: hair follicle |
Present |
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5L
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There is intense expression in the bulbs of developing tylotrich hair follicles.
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Specimen
Not shown:
embryonic day 17.0
(more )
Specimen
Not shown:
(close )
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Genetic Background:
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NMRI
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Age:
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embryonic day 17.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS25: skin |
Present |
Regionally restricted |
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Expression is present in the initiated epithelial placodes of the awl hairs.
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Specimen
7A:
embryonic day 15.0
(more )
Specimen
7A:
(close )
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Genetic Background:
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NMRI
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Age:
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embryonic day 15.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: skin |
Present |
Regionally restricted |
7A
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Expression is present in the basal epithelium of the placodes of the first wave of tylotrich hairs found on the back.
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Specimen
7B:
embryonic day 15.0; EdaTa/ EdaTa
(more )
Specimen
7B:
(close )
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Genetic Background:
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B6CBACa Aw-J/A-EdaTa/J-XO
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Mutant Allele(s):
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EdaTa/EdaTa
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Age:
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embryonic day 15.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: skin |
Present |
Regionally restricted |
7B
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The placodes have not been initiated, so expression is present throughout the ectoderm.
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Specimen
7C:
embryonic day 17.0
(more )
Specimen
7C:
(close )
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Genetic Background:
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NMRI
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Age:
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embryonic day 17.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS25: hair bulb |
Very strong |
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7C
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There is intense expression in the bulbs of developing tylotrich hair follicles.
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| TS25: skin |
Present |
Regionally restricted |
7C
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Expression is present in the placodes of awl follicles.
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Specimen
7D:
embryonic day 17.0; EdaTa/ EdaTa
(more )
Specimen
7D:
(close )
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Genetic Background:
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B6CBACa Aw-J/A-EdaTa/J-XO
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Mutant Allele(s):
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EdaTa/EdaTa
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Age:
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embryonic day 17.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS25: skin |
Very strong |
Regionally restricted |
7D
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There is intense expression in the placodes of awl follicles.
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Analysis Tools