Anxa7tm1Ngl
Targeted Allele Detail
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| Symbol: |
Anxa7tm1Ngl |
| Name: |
annexin A7; targeted mutation 1, Angelika A Noegel |
| MGI ID: |
MGI:2159006 |
| Synonyms: |
anxA7-, Anxa7- |
| Gene: |
Anxa7 Location: Chr14:20505328-20530201 bp, - strand Genetic Position: Chr14, 11.53 cM
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| Alliance: |
Anxa7tm1Ngl page
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Abnormal red blood cells in wild type and Anxa7tm1Ngl/Anxa7tm1Ngl mice
Show the 1 phenotype image(s) involving this allele.
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| Germline Transmission: |
Earliest citation of germline transmission:
J:69979
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| Parent Cell Line: |
D3 (ES Cell)
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| Strain of Origin: |
129S2/SvPas
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutation: |
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Insertion
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Mutation details: A neomycin selection cassette was inserted into exon 8. Northern blot analysis on RNA derived from various tissues of homozygous mice demonstrated that aberrant transcripts were produced from this allele. Western blot analysis on lysates derived from brain, heart, pancreas and skeletal muscle confirmed that no detectable protein is made from this allele.
(J:69979)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Anxa7 Mutation: |
38 strains or lines available
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| Original: |
J:69979 Herr C, et al., Loss of annexin A7 leads to alterations in frequency-induced shortening of isolated murine cardiomyocytes. Mol Cell Biol. 2001 Jul;21(13):4119-28 |
| All: |
9 reference(s) |
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Analysis Tools
