Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Neurod4tm1Kag
Name:	neurogenic differentiation 4; targeted mutation 1, Ryoichiro Kageyama
MGI ID:	MGI:2158737
Synonyms:	Math3-, Neurod4tm1Rka
Gene:	Neurod4  Location: Chr10:130104021-130116109 bp, - strand  Genetic Position: Chr10, 77.81 cM
Alliance:	Neurod4tm1Kag page

Germline Transmission:	Earliest citation of germline transmission: J:65410
Parent Cell Line:	TT2 (ES Cell)
Strain of Origin:	(C57BL/6NCrlj x CBA/JNCrlj)F1

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion   Mutation details: A neomycin cassette is inserted into the second exon of the wild-type gene. Northern analysis demonstrated a lack of gene specific mRNA in homozygous mutant animals. (J:65410)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	2 assay results
In Structures Affected by this Mutation:	5 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Neurod4 Mutation:	24 strains or lines available

Original:	J:65410 Tomita K, et al., Mammalian achaete-scute and atonal homologs regulate neuronal versus glial fate determination in the central nervous system. EMBO J. 2000 Oct 16;19(20):5460-72
All:	8 reference(s)