Summary | Mutation origin | Mutation description | Expression | Phenotypes | Tumor data | Find Mice (IMSR) | References

Symbol:	Ahrtm1Gonz
Name:	aryl-hydrocarbon receptor; targeted mutation 1, Frank J Gonzales
MGI ID:	MGI:2151800
Synonyms:	AhR-
Gene:	Ahr  Location: Chr12:35547978-35584988 bp, - strand  Genetic Position: Chr12, 15.78 cM
Alliance:	Ahrtm1Gonz page

Germline Transmission:	Earliest citation of germline transmission: J:25048
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     Exon 1 was replaced with a neomycin resistance gene. (J:25048)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

22 anatomical structure(s)

List all tumor models in MMHCdb carrying Ahrtm1Gonz

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ahr Mutation:	107 strains or lines available

Original:	J:25048 Fernandez-Salguero P, et al., Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor [see comments]. Science. 1995 May 5;268(5211):722-6
All:	75 reference(s)