Gene Expression Data
Assay Details
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Assay
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Reference:
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J:71034
Boyl PP, et al., Forebrain and midbrain development requires epiblast-restricted Otx2 translational control mediated by its 3' UTR. Development. 2001 Aug;128(15):2989-3000
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:2150148
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Gene symbol:
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Otx2
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Gene name:
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orthodenticle homeobox 2
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Results
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Specimen
7A wt:
embryonic day 8.5
(more  )
Specimen
7A wt:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 8.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
7B Otx2 l/l:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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Mutant Allele(s):
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Otx2tm2Asim/Otx2tm2Asim
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Age:
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embryonic day 8.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS13: future midbrain |
Present |
Non-Uniform |
7B
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Expression is present in an extended area compared to that seen in wild type but displaying two different levels of transcripts defined by two sharp borders of expression.
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| TS13: future prosencephalon |
Present |
Non-Uniform |
7B
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Expression is present in an extended area compared to that seen in wild type but displaying two different levels of transcripts defined by two sharp borders of expression.
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Specimen
7C Otx2 l/-:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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Mutant Allele(s):
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Otx2tm1Pas/Otx2tm2Asim
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Age:
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embryonic day 8.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS13: future brain |
Present |
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7C
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The area of expression in mutants is smaller than that seen in wild type.
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Analysis Tools