Gene Expression Data
Assay Details
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Assay
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Reference:
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J:60832
Pattyn A, et al., Control of hindbrain motor neuron differentiation by the homeobox gene Phox2b. Development. 2000 Apr;127(7):1349-58
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:2149603
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Gene symbol:
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Isl1
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Gene name:
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ISL1 transcription factor, LIM/homeodomain
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Probe:
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Isl1 probe2
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Results
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Specimen
2D:
embryonic day 10.5; Phox2btm1Jbr/Phox2b +
(more  )
Specimen
2D:
(close  )
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Genetic Background:
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Not Specified
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Mutant Allele(s):
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Phox2btm1Jbr/Phox2b+
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: hindbrain |
Present |
Regionally restricted |
2D
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Expression in all motor neuron precursors; restricted to postmitotic cells.
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Specimen
2D':
(close )
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Genetic Background:
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Not Specified
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Mutant Allele(s):
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Phox2btm1Jbr/Phox2btm1Jbr
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: future spinal cord |
Present |
Regionally restricted |
2D'
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Drastically reduced expression; restricted to somatic motor neurons of r5 and caudal rhombencephalon to cervical spinal cord.
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| TS17: hindbrain |
Present |
Regionally restricted |
2D'
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Drastically reduced expression; restricted to somatic motor neurons of r5 and caudal rhombencephalon to cervical spinal cord.
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| TS17: rhombomere 5 |
Present |
Regionally restricted |
2D'
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Drastically reduced expression; restricted to somatic motor neurons of r5 and caudal rhombencephalon to cervical spinal cord.
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Analysis Tools