Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol: Maftm1Glm Name: MAF bZIP transcription factor; targeted mutation 1, Laurie H Glimcher MGI ID: MGI:2148636 Synonyms: c-maf-, Maf- Gene: Maf  Location: Chr8:116429992-116433633 bp, - strand  Genetic Position: Chr8, 62.61 cM Alliance: Maftm1Glm page

Histological analysis of the lens from Maftm1Glm/Maf+ and Maftm1Glm/Maftm1Glm mice Show the 1 phenotype image(s) involving this allele.

Germline Transmission:	Earliest citation of germline transmission: J:54079
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion   Mutation details: Insertion of a neomycin cassette into the codon corresponding to amino acid 170 of the encoded protein. No protein was detected in kidney extracts derived from homozygous mice. (J:54079)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	24 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Maf Mutation:	26 strains or lines available

Original:	J:54079 Kim JI, et al., Requirement for the c-Maf transcription factor in crystallin gene regulation and lens development. Proc Natl Acad Sci U S A. 1999 Mar 30;96(7):3781-5
All:	13 reference(s)