Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Aplp2tm1Min
Name:	amyloid beta precursor-like protein 2; targeted mutation 1, Minoo Rassoulzadegan
MGI ID:	MGI:2138038
Gene:	Aplp2  Location: Chr9:31060853-31123111 bp, - strand  Genetic Position: Chr9, 16.66 cM, cytoband A2-B
Alliance:	Aplp2tm1Min page

Germline Transmission:	Earliest citation of germline transmission: J:49466
Parent Cell Line:	WW6 (ES Cell)
Strain of Origin:	STOCK 129/Sv and C57BL/6J and SJL

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin resistance cassette replaced sequences between exon 4 and exon 15, deleting 11.35 kb of the gene. (J:49466)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

2 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Aplp2 Mutation:	30 strains or lines available

Original:	J:49466 Rassoulzadegan M, et al., APLP2, a member of the Alzheimer precursor protein family, is required for correct genomic segregation in dividing mouse cells. EMBO J. 1998 Aug 17;17(16):4647-56
All:	2 reference(s)