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Gene Expression Data
Assay Details
Assay
Reference: J:69854 Liu C, et al., Regulation of left-right asymmetry by thresholds of Pitx2c activity. Development. 2001 Jun;128(11):2039-48
Assay type: RNA in situ
MGI Accession ID: MGI:2137251
Gene symbol: Pitx2
Gene name: paired-like homeodomain transcription factor 2
Probe: Pitx2c
Probe preparation: Antisense RNA
Assay notes: For these in situs hybridizations, a c isoform specific probe was used.
Results
Specimen 1. A.: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: lateral plate mesoderm Present Regionally restricted 1A Present only on the left side.
TS13: splanchnopleure Present Regionally restricted 1A Present only on the left side.

Specimen 1. C.: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS15: mesenchyme derived from splanchnopleure Present Regionally restricted 1C Present only on the left side.
TS15: embryo Present Regionally restricted 1C Present in the developing body wall.

Specimen 1. D.: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: sinus venosus left horn Present 1D
TS17: left lung rudiment Present 1D
TS17: gut Present Regionally restricted 1D Present on the left side of the gut.
TS17: stomach Present 1D
TS17: hindgut diverticulum Present 1D Present in the cecal diverticulum.
TS17: midgut Present 1D Present in the duodenum and the midgut.

Specimen 1. E.: embryonic day 10.5; Pitx2tm2.1Jfm/Pitx2tm2.1Jfm (more )
Structure Level Pattern Image Note
TS17: left lung rudiment Present 1E
TS17: gut Present Regionally restricted 1E Present on the left side of the gut.

Specimen 1. G.: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: oral epithelium Present 1G
TS17: extraembryonic component Present Regionally restricted 1G Present in umbilical structures.
TS17: eye Present 1G
TS17: embryo Present Regionally restricted 1G Present in the developing body wall.

Specimen 4. K.: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: foregut duodenum Present Regionally restricted 4K Present on the left side only.

Specimen 4. L.: embryonic day 12.5; Pitx2tm1Jfm/Pitx2tm2Jfm (more )
Structure Level Pattern Image Note
TS20: foregut duodenum Present 4L

Specimen 4. M.: embryonic day 12.5; Pitx2tm1Jfm/Pitx2tm2.1Jfm (more )
Structure Level Pattern Image Note
TS20: foregut duodenum Present 4M


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory